At the Mission Innovation Annual Gathering 2025 held in Seoul, South Korea from April 9–11, India reaffirmed its commitment to clean energy innovation by spotlighting its BioE3 Policy and Integrated Biorefinery Mission. Led by the Department of Biotechnology (DBT), India co-chairs the Mission Integrated Biorefinery along with the Netherlands under the broader Mission Innovation (MI) 2.0 platform. The gathering brought together international stakeholders to discuss collaborative solutions for clean energy. India’s BioE3 Policy (Biotechnology for Environment, Energy, and Economy) was presented as a strategic framework to promote low-carbon, sustainable manufacturing of fuels, chemicals, and materials through biotechnology. DBT emphasised India’s focus on Carbon Capture, Utilisation, and Bioenergy (CCUB) integration to enhance the biomanufacturing of clean fuels and green chemicals. The policy supports innovation-driven, eco-friendly technologies aimed at addressing climate change and aligning with national decarbonisation priorities. India also participated in roundtables and technical sessions that explored research, development, and demonstration (RD&D) opportunities in biomass-based manufacturing. Delegates engaged in knowledge-sharing visits to clean energy facilities, including Hanyang University and the Korea Institute of Science and Technology, with coordination support from the Indian Embassy in Seoul. India’s contribution highlighted its leadership in bioinnovations for energy transition, reinforcing the potential for global partnerships in clean biotechnology under the Mission Innovation umbrella. (PIB)